Peer-reviewed publications
Cohrt KAO, Marín L, Kjellerup L, Clausen JD, Dalby-Brown W, Calera JA, Winther AL.Novel Zinc-Attenuating Compounds as Potent Broad-Spectrum Antifungal Agents with In Vitro and In Vivo Efficacy. Antimicrob Agents Chemother. 2018 Apr 26;62(5):e02024-17. doi: 10.1128/AAC.02024-17. PMID: 29439980; PMCID: PMC5923171.
Bublitz M, Kjellerup L, Cohrt KO, Gordon S, Mortensen AL, Clausen JD, Pallin TD, Hansen JB, Fuglsang AT, Dalby-Brown W, Winther AL. Tetrahydrocarbazoles are a novel class of potent P-type ATPase inhibitors with antifungal activity. PLoS One. 2018 Jan 2;13(1):e0188620. doi: 10.1371/journal.pone.0188620. PMID: 29293507; PMCID: PMC5749684.
Clausen JD, Kjellerup L, Cohrt KO, Hansen JB, Dalby-Brown W, Winther AL. Elucidation of antimicrobial activity and mechanism of action by N-substituted carbazole derivatives. Bioorg Med Chem Lett. 2017 Oct 1;27(19):4564-4570. doi: 10.1016/j.bmcl.2017.08.067. Epub 2017 Sep 1. PMID: 28893470; PMCID: PMC5609566.
Kjellerup L, Gordon S, Cohrt KO, Brown WD, Fuglsang AT, Winther AL. Identification of Antifungal H+-ATPase Inhibitors with Effect on Plasma Membrane Potential. Antimicrob Agents Chemother. 2017 Jun 27;61(7):e00032-17. doi: 10.1128/AAC.00032-17. PMID: 28438931; PMCID: PMC5487681.
Sapkota R, Knorr K, Jørgensen LN, O'Hanlon KA, Nicolaisen M. Host genotype is an important determinant of the cereal phyllosphere mycobiome. New Phytol. 2015 Sep;207(4):1134-44. doi: 10.1111/nph.13418. Epub 2015 Apr 21. PMID: 25898906.
Klein DK, Hoffmann S, Ahlskog JK, O'Hanlon K, Quaas M, Larsen BD, Rolland B, Rösner HI, Walter D, Kousholt AN, Menzel T, Lees M, Johansen JV, Rappsilber J, Engeland K, Sørensen CS. Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control. Nat Commun. 2015 Jan 5;6:5800. doi: 10.1038/ncomms6800. PMID: 25557911.
EP Zida, IG Thio, BJ Néya, K O'Hanlon, LC Deleuran, EG Wulff, OS Lund. Fungal endophytes of sorghum in Burkina Faso: occurrence and distribution. African Journal of Microbiology Research. 2014. 8(46), 3782-3793.
KA O’Hanlon*, K Knorr, LN Jørgensen, M Nicolaisen, B Boelt. Exploring the potential of symbiotic fungal endophytes in cereal disease suppression. Biological Control. 2012. 63 (2), 69-78. *Corresponding author.
Beck H, Nähse-Kumpf V, Larsen MS, O'Hanlon KA, Patzke S, Holmberg C, Mejlvang J, Groth A, Nielsen O, Syljuåsen RG, Sørensen CS. Cyclin-dependent kinase suppression by WEE1 kinase protects the genome through control of replication initiation and nucleotide consumption. Mol Cell Biol. 2012 Oct;32(20):4226-36. doi: 10.1128/MCB.00412-12. Epub 2012 Aug 20. PMID: 22907750; PMCID: PMC3457333.
O'Hanlon KA, Margison GP, Hatch A, Fitzpatrick DA, Owens RA, Doyle S, Jones GW. Molecular characterization of an adaptive response to alkylating agents in the opportunistic pathogen Aspergillus fumigatus. Nucleic Acids Res. 2012 Sep;40(16):7806-20. doi: 10.1093/nar/gks522. Epub 2012 Jun 4. PMID: 22669901; PMCID: PMC3439912.
O'Hanlon KA, Gallagher L, Schrettl M, Jöchl C, Kavanagh K, Larsen TO, Doyle S. Nonribosomal peptide synthetase genes pesL and pes1 are essential for Fumigaclavine C production in Aspergillus fumigatus. Appl Environ Microbiol. 2012 May;78(9):3166-76. doi: 10.1128/AEM.07249-11. Epub 2012 Feb 17. PMID: 22344643; PMCID: PMC3346476.
O'Hanlon KA, Cairns T, Stack D, Schrettl M, Bignell EM, Kavanagh K, Miggin SM, O'Keeffe G, Larsen TO, Doyle S. Targeted disruption of nonribosomal peptide synthetase pes3 augments the virulence of Aspergillus fumigatus. Infect Immun. 2011 Oct;79(10):3978-92. doi: 10.1128/IAI.00192-11. Epub 2011 Jul 11. PMID: 21746855; PMCID: PMC3187245.
Additional works:
Book Chapter: Virulence characteristics of Aspergillus fumigatus. RA Owens, G O'Keeffe, KA O'Hanlon, L Gallagher, S Doyle. Book Chapter 8 in: Human pathogenic fungi: molecular biology and pathogenic mechanisms, 163-194. Caister Academic Press.
PhD Thesis: O'Hanlon, Karen (2010). A functional genomics approach: Characterisation of two Non-ribosomal peptide synthetase genes, and investigation of an adaptive response towards alkylating DNA damage in Aspergillus fumigatus.